Distant recurrence (metastasis) occurs when cancer spreads beyond the breast and nearby lymph nodes to other organs such as the bones, liver, lungs or brain. The risk of distant recurrence is the same for people who have lumpectomy plus radiation therapy and those who have mastectomy [ 132 ]. Breast cancer can come back as a local recurrence (meaning in the treated breast or near the mastectomy scar) or somewhere else in the body. Some of the most common sites of recurrence outside the breast are the lymph nodes, bones, liver, lungs, and brain.
The Rates Now Better in 'Modern Era' of Treatment. Until now, the local recurrence rates were 5% to 10% following lumpectomy. These rates reflect historic data associated with the use of older breast cancer treatment protocols, according to a research team led by Heather B. Neuman, MD, of the University of Wisconsin School of Medicine and Public Health, Madison. Jun 16, 2011 · This retrospective analysis included 6,135 consecutive unilateral breast cancer patients undergoing surgery in 1998–2008, with 847 lumpectomy patients and 5,288 mastectomy patients. Recurrence patterns were scrutinized and annual recurrence rates were calculated.Cited by: 11.
Breast Cancer Lumpectomy Margins local recurrence rates, randomized controlled trials on rates of margin re-excision with Using re-excision lumpectomy rate a measure of quality: The use of margin status and RELR as a measure of quality is controversial. 4,9,14,15. Looking at the data another way, the annual rate of an invasive breast cancer recurrence was reduced from approximately 2.6% to 0.6% (a 76% relative risk reduction [P recurrence are likely to be at a higher risk of death from distant metastases than those who have a recurrence of DCIS, this is an interesting observation.Cited by: 11.
As the researchers expected, the annual rates of death from breast cancer were low during the first 5 years after initial diagnosis. But after year 5, the annual rates of death from breast cancer and distant recurrence were similar. Specific 20-year risks of death from breast cancer were: 15% for women with zero positive lymph nodes. This study found that the risk of invasive breast cancer after a diagnosis of low-risk DCIS treated with lumpectomy alone ranged from 7.5% to 13.4%. Some women may find that risk acceptable. Other women may find that risk unacceptable and want more treatments after surgery.
Local breast cancer recurrence is when the cancer has reoccurred close to or in the same place the first tumor was found within the breast. If you were treated with lumpectomy and radiation for your first occurrence, the breast tissue cannot be treated with radiation again.